Improved Cellular Delivery

EUFECT is a state-of-the-art platform for lipid nanoparticles (LNPs) used in cell transfection. Our EUFECT products are characterized by high transfection efficiency and low toxicity across a wide range of cell lines. We use proprietary ionizable lipids in combination with optimized formulations and continuously refine our EUFECT products to better meet our customers’ needs. To round out our range of services, we also offer to work closely with you to develop solutions for your LNP-based application. The EUFECT brand is backed by a consortium comprising the owner-managed company CHESS Chemische Entwicklungs- und Synthese-Service GmbH (CHESS) and the private research institute Steinbeis-Innovationszentrum Zellkulturtechnik (SIZ), both based in Mannheim. Our diverse expertise in the fields of cell biology and medicinal chemistry dates back more than 30 years and complement each other exceptionally well in the field of LNP-based cell transfection. The development of new lipids and reagents at CHESS and rapid testing on cells at SIZ enable effective product development, which has led to promising products since the start of our collaboration in this field in 2025. In addition, we maintain international contacts with research groups that test our products in their respective fields of research and provide us with feedback on their results using our reagents.

Explore Products View Research Data

Product Development

EB

Eufect Blue

High-efficiency lipid for enhanced cellular uptake

  • Superior transfection efficiency
  • For rapidly proliferating cells
ER

Eufect Red

Specialized formulation for targeted delivery

  • For slow proliferating cells
  • Low toxicity
EG

Eufect Gold

Specialized formulation for targeted delivery

  • Very low toxicity
  • For sensitive cells
  • Reduced stress

Research Data

Comprehensive testing across multiple cell types demonstrates superior performance of Eufect products.

Some Tested Cell Lines

SK-BR-3

Human breast carcinoma cell line

SAOS-2

Human osteogenic sarcoma cell line

MDA-MB-231

Human breast carcinoma cell line

MC3T3

Mouse osteoblast precursor cell line

MCF-7

Human breast adenocarcinoma cell line



Flow Cytometry Analysis

Quantitative transfection efficiency was determined by flow cytometry. Representative histograms demonstrate increased mean fluorescence intensity for Eufect Blue, Red and Eufect Gold.

EUFECT flow cytometry and fluorescence microskopy against SM-102 and C12-200

Flow Cytometry Analysis / Fluorescence Microscopy

Quantitative assessment of transfection efficiency using flow cytometry demonstrates improved performance of Eufect lipides across many tested cell lines. High-resolution imaging confirms cellular uptake and localization patterns. Phase-contrast microscopy reveals cell morphology, monolayer density, and integrity — confirming viability independent of transfection status

Physicochemical Characterisation — ZetaView® (Particle Metrix)

All EUFECT LNP batches are characterised by Nanoparticle Tracking Analysis (NTA) using the ZetaView® system (Particle Metrix). By tracking individual particle Brownian motion under laser illumination, NTA simultaneously delivers three critical parameters from a single measurement run.